You will find a bunch of safes in Resident Evil Requiem. You don’t have to unlock them all because no required quest item is inside one. Still, you can get ammo, collectibles, and lore related items inside safes.
Combinations for these safes are tiny puzzles you can solve but if you just want to be quick, below is the complete list of safe codes in Resident Evil Requiem. Here is a quick table you can use:
| Safe Location | Code |
| 2F Bar & Lounge – West Wing Care Center | 10L – 80R – 30L |
| Examination Room – East Wing Care Center | 30R – 10L – 50R |
| Basement – Underground Care Center | 60R – 40L – 80R |
| Sterilization Room – ARK | 10R – 90L – 20R |
| Monitor Control Room – ARK | 50L – 60R – 80L |
Bar & Lounge Safe Code

- Safe Location: Rhodes Hill Care Center, West Wing, 2F
- Safe Code: 10 left, 80 right, and 30 left
The Bar and Lounge safe code is printed on a note you can find inside the Custodian’s Office West Wing of Rhodes Hill Care Center. To access this office, you need a Security Level 1 Keycard from a body in the upstairs corridor in the East Wing.
Examination Room Safe Code

- Safe Location: Rhodes Hill Care Center, East Wing, 1F
- Safe Code: 30 right, 10 left, and 50 right
The Examination Room Safe Code is a printed paper that is found in the locker area outside the Conference Room in the East Wing of Rhodes Hill Care Center.
Basement Safe Code

- Safe Location: Rhodes Hill Care Center Basement
- Safe Code: 60 right, 40 left, and 80 right
The Base Safe Code is inside one of the Warped Closets you come across while playing as Leon, after Grace enters the basement to look for Emily.
Sterilization Chamber Safe Code

- Safe Location: ARK
- Safe Code: 10 right, 90 left, and 20 right
The Sterilization Chamber Safe Code is found in the Bioweapon Repository 05 of the ARK building after finding the safe.
Monitor Control Room Safe Code

- Safe Location: ARK
- Safe Code: 50 right, 60 left, and 80 right
The Monitor Control Room Safe Code is also found inside the Bioweapon Repository 05 of the ARK building.









